DNA METHYLATION and DEMETHYLATION IMBALANCE in CANCER [ 2015 - 2017 ]

Research Grant

Researchers: Prof Susan Clark (Principal investigator) ,  Dr Clare Stirzaker

Brief description This study will give us new insights into the role of MBD2 and TET proteins in establishing the epigenome and especially will have a major impact in our understanding of the key steps involved in both de novo DNA methylation and demethylation in cancer. Ultimately these new understandings may provide routes to use MBD2 and/or TET proteins as pharmacological targets in cancer treatment.

Funding Amount $AUD 635,443.92

Funding Scheme Project Grants

Notes Standard Project Grant