Distribution of neurotransmitter receptors on identified cell populations in the primate retina [ 2001 - 2003 ]

Research Grant

Researchers: Dr Ulrike Gruenert (Principal investigator) ,  Prof Paul Martin

Brief description Neurons (nerve cells) communicate with each other by releasing chemicals called neurotransmitters at specialized sites called synapses. Each neuron has synaptic receptors, which determine how it will respond to neurotransmitters released by other neurons. The molecular structure and function of these receptors is well understood. Much less is known about the rules that govern which receptor types are expressed by each type of neuron, and how these receptors are distributed to the appropriate synapses so as to allow the normal function of the nervous system. We will study the distribution of neurotransmitter receptors on identified neurons in the retina. The retina is part of the central nervous system and its highly ordered structure makes it an ideal model nervous system. We will compare the distribution of receptors on neurons that play distinct functional roles in colour and movement detection. These experiments will advance our understanding of the normal functioning of the nervous system.

Funding Amount $AUD 421,812.54

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant