grant

Dissecting TAF5L and TAF6L functions in embryonic stem cells, reprogramming and neurodevelopment [ 2019 - ]

Also known as: 5314184

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/GNT1159461]

Brief description Our CRISPR-Cas9 mediated loss-of-function genetic screen identifies two new candidate epigenetic regulators- TAF5L and TAF6L- for maintenance of the mouse ESC state. In this proposed research, we will aim- 1) to dissect the detail molecular functions of TAF5L and TAF6L in mouse ESCs; 2) to examine the role of TAF5L and TAF6L in induced pluripotent stem cells (iPSCs) generation, and 3) to investigate the role of TAF5L and TAF6L in neurodevelopment.

Funding Amount $691,653.00

Funding Scheme Project Grants

Notes New Investigator Grant

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Identifiers
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ACN 633 798 857