Dissecting a Serial Killer: Investigating the Degranulation Pathways in Cytotoxic Lymphocytes [ 2014 - 2016 ]

Research Grant

Researchers: A/Pr Ilia Voskoboinik (Principal investigator) ,  Dr Jamie Lopez

Brief description When cells of the human body become cancerous or infected with virus, the body's immune system engages cytotoxic lymphocytes, known as "killer cells", that secrete an auxiliary of toxic proteins to eliminate these cells. The aim of this study is to investigate the mechanisms by which these critical immune cells accomplish this task. Importantly, humans who are genetically lacking in critical constituents of the cytotoxic lymphocyte are less able to fight off a viral infection and may be at a higher risk of developing cancer.

Funding Amount $AUD 604,459.53

Funding Scheme Project Grants

Notes Standard Project Grant