Dissecting the molecular basis of actin filament disassembly in the malaria parasite [ 2012 - 2015 ]

Research Grant

Researchers: Dr Jacqueline Gulbis (Principal investigator) ,  Dr Jake Baum (Principal investigator) ,  Dr Wilson Wong

Brief description Cell movement by the malaria parasites is fundamental to parasite infection and disease. However, whilst core components of the parasite motor driving movement are known, little is understood about their regulation, in particular actin – the dynamic force behind all parasite motility. Here by dissecting the role of actin-depolymerizing-factor-1, an essential parasite actin regulator, we hope to reveal one of the central processes that underlies motility and develop it into a potential drug target.

Funding Amount $AUD 576,715.97

Funding Scheme Project Grants

Notes Standard Project Grant