Dissecting the function and therapeutic potential of Hedgehog signaling in breast cancer [ 2013 - 2016 ]

Research Grant

Researchers: A/Pr Alexander Swarbrick (Principal investigator)

Brief description Breast cancer cells create the conditions for their own survival by communicating their needs with to the healthy cells that surround them. We have previously shown that a molecule known as ‘hedgehog’ transmits biochemical signals between the cancer cells and healthy cells. When hedgehog is ‘silenced’, tumours shrink and stop their spread. In this application, we explore the fundamental biology of Hedgehog signaling and its potential as a drug target for breast cancer.

Funding Amount $AUD 459,270.32

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF