grant

Dissecting commitment to apoptosis [ 2009 - 2011 ]

Also known as: How the Bak protein mediates apoptotic cell death, including death of cancer cells

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/575559]

Researchers: Dr Ruth Kluck (Principal investigator) ,  Dr Jacqueline Gulbis (Contains) ,  Prof Jerry Adams

Brief description In cancer cells the normal process of cell death (called apoptosis) is defective, helping abnormal cells to grow and multiply unchecked. The Bak protein is a member of the Bcl-2 family of apoptosis regulators, and plays a pivotal role in mediating cell death. By defining each step in Bak-mediated apoptosis, we aim to better understand how cancer cells accumulate, and how targeting the Bcl-2 family may lead to effective anti-cancer therapeutics.

Funding Amount $AUD 582,515.50

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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