grant

Dissecting catalysis and inhibition of a unique endo-acting mannose-processing glycosidase [ 2012-04-01 - 2015-03-31 ]

Research Grant

[Cite as https://purl.org/au-research/grants/arc/DP120101396]

Researchers: Spencer Williams (Chief Investigator) ,  Prof Gideon Davies (Partner Investigator)

Brief description Dissecting catalysis and inhibition of a unique endo-acting mannose-processing glycosidase. Defects in the attachment of carbohydrates to proteins are a hallmark of diseases such as cancer and viral infection. This project will dissect the molecular details of the bond-making and breaking steps that occur during the synthesis of glycoproteins assisting in the development of innovative new drugs.

Funding Amount $360,000

Funding Scheme Discovery Projects

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