Dissecting catalysis and inhibition of a unique endo-acting mannose-processing glycosidase [ 2012 - 2014 ]

Research Grant

Researchers Dr Spencer John Williams; Prof Gideon Davies

Brief description Defects in the attachment of carbohydrates to proteins are a hallmark of diseases such as cancer and viral infection. This project will dissect the molecular details of the bond-making and breaking steps that occur during the synthesis of glycoproteins assisting in the development of innovative new drugs.

Funding Amount $360,000

Funding Scheme Discovery Projects