Dissecting BORIS Function In Neoplasia [ 2008 - 2008 ]

Research Grant

Researchers: Prof John Rasko (Principal investigator) ,  A/Pr Jeffrey Holst

Brief description An understanding of the way cells control their complex internal circuitry is relevant to diseases like cancer and leukemia. The main focus of this project is a cellular regulator we identified several years ago called BORIS. Normally dormant in all cells outside the male reproductive organs, BORIS is reactivated in many cancers. We will study the network of factors perturbed when BORIS becomes inappropriately active in cancer cells. Ultimately this project may lead to new treatments for cancer.

Funding Amount $AUD 186,550.00

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant