grant

Dissecting BAFF Receptor Signals: Key Mediators of B-Lymphocyte Survival and Autoimmune Disease [ 2009 - 2014 ]

Also known as: BAFF Receptor and B-Cell Survival

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/541951]

Researchers: Dr Joanne Hildebrand (Principal investigator)

Brief description B-Cells of the immune system need a growth factor named 'BAFF' to grow and survive. Elevated levels of BAFF have been detected in patients suffering from autoimmune diseases like lupus and arthritis, and B-Cell cancers like myeloma. This study will determine the identity of the chemical messages that BAFF sends to B-Cells, and how these facilitate B-Cell growth and survival. This will provide a framework for the design of targeted drug therapies that reduce the severity of BAFF related diseases.

Funding Amount $AUD 376,165.85

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF

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Identifiers
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ACN 633 798 857