Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP200102837]Researchers: Dr Frank Sainsbury (Chief Investigator) , Dr Frank Sainsbury (Chief Investigator) , ELIZABETH GILLAM (Chief Investigator) , Colin Scott (Partner Investigator) , Trevor Douglas (Partner Investigator)
Brief description Nano-reactors: Protein cages as reusable scaffolds for designer enzymes. This project aims to develop robust protein cages derived from the coats of viruses to contain heat-stable P450 enzymes, for use as specialised protein bio-catalysts in chemical industries. A valuable chemical precursor of renewable bio-plastics will be produced from seed oils by enzymes, reducing the use of fossil fuels. This synthetic biology approach combines biotechnology, nanotechnology and protein engineering to establish a plant-based platform biotechnology for using enzymes as catalysts to make high-value molecules. The project aims to show how to engineer clean, sustainable chemistry in designer nano-environments. This should make synthetic processes more sustainable and enhance advanced chemical manufacturing in Australia.
Funding Amount $451,284
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP200102837
- ARC : DP200102837