Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP200101658]Researchers: Distinguished Professor Dietmar Hutmacher (Chief Investigator) , Dr Laura Bray (Chief Investigator) , Dr Nathalie Bock (Chief Investigator) , Yi-Chin Toh (Chief Investigator)
Brief description A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interactions, which will greatly complement existing meta-omics approaches. The deliverables include a proof-of-concept system validated for gut-liver axis as well as the creation of new knowledge and framework to assimilate design thinking and advanced manufacturing to elevate tissue engineering into physiology engineering.
Funding Amount $390,000
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP200101658
- ARC : DP200101658