Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP180102987]Researchers: Dr Begona Heras (Chief Investigator) , Prof Mark Schembri (Chief Investigator)
Brief description How auto-transporter proteins mediate bacterial interactions. This project aims to investigate the structure-function relationships that underpin key auto-transporter roles in bacterial cell adhesion, aggregation and biofilm formation. Auto-transporter proteins are extremely common in bacteria where they play a central role in controlling bacterial interactions with other bacteria, with human cells, and with surfaces. This project will define the molecular mechanisms underlying these processes. This will have significant benefits, such as providing the basis for the development of approaches to block auto-transporter functions that contribute to the establishment of persistent and difficult to treat bacterial infections.
Funding Amount $477,446
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP180102987
- ARC : DP180102987