[Cite as http://purl.org/au-research/grants/arc/DP170100781]
Prof Lars Ittner
Brief description The tau interactome. This project aims to decipher tau-dependent mechanisms at the molecular level to understand its pivotal role in neuronal integrity and function. Tau is a predominantly axonal protein with microtubule stabilising properties and has been implicated in several neurodegenerative disorders, including Alzheimer’s disease. Knowledge of its other physiological roles in the brain is limited, although it seems to be involved in signalling processes. The expected outcome of this study is a deeper understanding of brain function during development and aging, which may ultimately contribute to new preventive treatments and medical care strategies.
Funding Amount $518,500
Funding Scheme Discovery Projects
View this grant in the ARC Data Portal