Discovery Projects - Grant ID: DP160103100 [ 2016-01-01 - 2019-06-01 ]

Research Grant

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Researchers: Dr Nicholas Hamilton (Chief Investigator) ,  Prof Ian Smyth (Chief Investigator) ,  Mark Henkelman (Partner Investigator)

Brief description Morphological development of the kidney – a paradigm for organogenesis. This project aims to shed new light on how the kidney develops, how normal adult function is established and how congenital kidney malformations occur. It aims to investigate a mathematical pattern that has been discovered in the program of branching morphogenesis which dictates kidney development. By combining cutting-edge genetic approaches, morphological analysis and mathematical modelling, this project plans to explore how this pattern is established, how it dictates kidney development and whether it constitutes an ancient mechanism central to organ formation. Project outcomes may improve understanding of fundamental developmental processes and developmental disease and variation. Project findings may also be important for understanding the development of other organ systems.

Funding Amount $488,100

Funding Scheme Discovery Projects

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