Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP150104358]
Researchers:
A/Prof Ross McGeary
(Chief Investigator)
,
Prof David Ollis
(Chief Investigator)
,
Professor Gary Schenk
(Chief Investigator)
,
Professor Gary Schenk
(Chief Investigator)
,
Professor Luke Guddat
(Chief Investigator)
View all 7 related researchers
Brief description Harnessing the potential of metals in biocatalysis. The project aims to use an integrated, multi-disciplinary approach to study the properties of a group of related but functionally diverse enzymes; binuclear metallohydrolases (BMHs). These enzymes are of great relevance to protein engineers aiming to produce potent agents for bioremediation and pharmacologists interested in developing drugs. Elucidating and modulating the mode of action of BMHs is thus our main objective and should provide essential information to fully exploit the potential of these enzymes for practical applications. In particular, understanding how metal ions interact with BMHs and how this contributes to their reactivity is crucial to optimally understand their biotechnological potential.
Funding Amount $429,100
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP150104358
- ARC : DP150104358