Research Grant
[Cite as http://purl.org/au-research/grants/arc/DP150104321]Researchers: Dr Janet van Eersel (Chief Investigator) , Prof Peter Gunning (Chief Investigator) , Thomas Fath (Chief Investigator) , Yazi Ke (Chief Investigator)
Brief description The role of LIM Kinase 1 in neurons. The aim of this project is to study LIM domain kinase 1 in neuronal function, using cell and mouse models. Unrestricted brain function is essential to one’s wellbeing and the ability to perform normally. Critically contributing to the function of neurons is a cytoskeleton which maintains morphology and function. However, molecular mechanisms underlying cytoskeletal dynamics are poorly understood. LIM domain kinase 1, a key regulator of the actin cytoskeleton decreased with age and its loss associated with deficits in memory and neuronal morphology. This project could reveal fundamental processes regulating and maintaining brain function.
Funding Amount $445,500
Funding Scheme Discovery Projects
- ARC : DP150104321
- PURL : http://purl.org/au-research/grants/arc/DP150104321
