Discovery Projects - Grant ID: DP150101674 [ 2015-03-17 - 2020-07-31 ]

Research Grant

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Researchers: Dr Bryan Coad (Chief Investigator) ,  Prof Hans Griesser (Chief Investigator) ,  Prof Harm-Anton Klok (Partner Investigator) ,  Prof Nick Read (Partner Investigator)

Brief description Combating fungal biofilm growth on surfaces. This project aims to establish a scientific basis for the design and development of thin coatings, for use on biomedical devices, that can resist the attachment of fungal cells and the ensuing formation of infectious fungal biofilms on their surfaces. Advancing mechanistic understanding of how physico-chemical properties of materials surfaces influence fungal attachment will enable rational development and optimisation of coating chemistries and structures. Tethered antifungal compounds will be added to polymer surfaces by controlled polymerisation methods to provide active deterrence; factors such as conformational flexibility will be studied to optimise coatings, which may will prevent life-threatening infections and reduce healthcare costs.

Funding Amount $355,500

Funding Scheme Discovery Projects

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