Discovery of New Tuberculosis Drug Leads Targeting Cell Wall Biosynthesis [ 2015 - 2017 ]

Research Grant

Researchers: Prof Richard Payne (Principal investigator) ,  Dr Nicholas West ,  Prof Susan Charman ,  Prof Warwick Britton

Brief description There is a desperate need for the development of new therapies for the treatment of TB due to widespread resistance of Mycobacterium tuberculosis, the causative agent of TB, to current therapies. The overall goal of this research project is to identify new TB drug leads through the development of structural analogues of bacterially-derived natural products called the sansanmycins that inhibit cell wall synthesis in Mycobacterium tuberculosis.

Funding Amount $AUD 714,815.97

Funding Scheme Project Grants

Notes Standard Project Grant