grant

Discovery Early Career Researcher Award - Grant ID: DE190100116 [ 2019-01-01 - 2021-12-31 ]

Research Grant

[Cite as https://purl.org/au-research/grants/arc/DE190100116]

Researchers: Dr Quan Nguyen (Discovery early Career Researcher Award) ,  Dr Quan Nguyen (Discovery early Career Researcher Award)

Brief description Cell types and cell states revealed by single-cell regulatory networks. This project aims to use single-cell gene regulation networks to predict cell types. Computational approaches are needed to recapitulate how the over 37 trillion cells program the shared genome sequence in a human body to create astoundingly diverse forms and functions. This project integrates millions of high-resolution single-cell gene expression profiles with large-scale population regulatory data to systematically reconstruct gene regulatory networks. These networks are the molecular basis for understanding human cells. This projects outcomes intend to include the first reference single-cell regulatory database and novel methods and software to predict individual cells. This project will contribute to advancing Australia's capabilities in single-cell, precision medicine, and big biological data analysis leading to significant scientific, societal and commercial benefits.

Funding Amount $415,737

Funding Scheme Discovery Early Career Researcher Award

View this grant in the ARC Data Portal

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