Research Grant
[Cite as https://purl.org/au-research/grants/arc/DE160101142]Researchers: Dr Eivind Undheim (Discovery Early Career Researcher Award) , Dr Eivind Undheim (Discovery Early Career Researcher Award)
Brief description Unravelling the structural evolution of centipede toxins. The project intends to improve understanding of venom evolution in centipedes, and uncover new families of peptides with potential application in the agrochemical and pharmaceutical sectors. Venoms have emerged as a rich source of pharmacological tools with potential for development into therapeutics and bioinsecticides. However, venoms-based discovery has been limited by the narrow taxonomical range studied, and many groups of venomous animals remain overlooked. One such group is centipedes, whose venoms contain diverse novel toxins. This project aims to provide an insight into centipede toxin evolution, and establish a structure-based approach to understanding their evolution and structural diversification. The outcomes may contribute to our understanding of protein evolution and support the development of new products.
Funding Amount $360,000
Funding Scheme Discovery Early Career Researcher Award
- PURL : https://purl.org/au-research/grants/arc/DE160101142
- ARC : DE160101142