[Cite as http://purl.org/au-research/grants/arc/DE160100900]
Researchers Dr Ha Lien Phuong Tran
Brief description This project aims to develop guided novel nanomaterials as a new biotechnological platform for in vivo targeted delivery of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) for gene editing. By systematically engineering the surface properties of natural nanovesicles known as exosomes, a novel nanotechnology platform should be established. The guided nano biotechnological platform should not only enable targeted in vivo precision gene editing via CRISPR but also specific delivery of gene editing machinery across the blood brain barrier for better exploration of fundamental biology of the brain.
Funding Amount $366,000
Funding Scheme Discovery Early Career Researcher Award