grant

Directed evolution of AAV capsid variants for enhanced targeted genome editing in the human liver [ 2016 - ]

Also known as: 5187184

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/GNT1108311]

Researchers: Dr Leszek Lisowski (Principal investigator) ,  Prof Hung Fat Tse Prof Ian Alexander

Brief description Liver transplantation is often the only treatment option available for patients with severe liver disease, and is complicated by a shortage of donor organs and the need for life-long drug therapy to prevent rejection. Repair of a patient’s own liver by gene therapy is a promising alternative. This project focuses on developing the technology required to undertake precise correction of genetic spelling errors in diseased liver cells without the need to first remove them from the body.

Funding Amount $386,012.00

Funding Scheme Project Grants

Notes Standard Project Grant

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