Dihydroceramide Desaturase-1 (Des1) Inhibitors for the Treatment of Fibrotic Disease [ 2019 - ]

Research Grant

Researchers: A/Pr Bernard Flynn (Principal investigator) ,  A/Pr Bing Wang ,  Prof Christopher Reid ,  Prof Darren Kelly ,  Prof Stuart Pitson

Brief description Fibrotic disease is characterised by excessive scarring and tissue hardening leading to organ failure and accounts for approximately 43% of deaths from disease in the developed world, representing a major unmet medical need. Our group has identified a novel biological target and associated drug molecules for the treatment of fibrosis. In this project we will provide a preclinical proof-of-concept concept in animal models for our drug molecules to attract ongoing commercial support.

Funding Amount $680,825.00

Funding Scheme Development Grants

Notes Development Grant