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diceCT imaging of the ZIKV mouse brain during development

Flinders University
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.25451/flinders.26086651.v1&rft.title=diceCT imaging of the ZIKV mouse brain during development&rft.identifier=https://doi.org/10.25451/flinders.26086651.v1&rft.publisher=Flinders University&rft.description=The study aimed to investigate the utility of diceCT in detecting morphological changes with ZIKV-infection during development. The study used a previously published mouse model (Cowell, et al., 2023, DOI: 10.1007/s13365-023-01123-5), and has extended this to 10 dpi, equating to P4, P7 and P11 of mouse development. A file with the protocol for diceCT staining and imaging is herein. This Figshare site also contains images from diceCT scans of the brains of neonatal mice, compiled into videos (development - ui, ZKIV - containing 3, 6 and 10 dpi from individual uninfected and ZIKV mice; and unknown mixed cohort folders - from one litter with 3 ui and 4 ZIKV animals, in a blinded fashion). The computational segmenting and volume analysis performed on the brains is also available in a separate folder for both of these.All original diceCT images are available on request.&rft.creator=Anonymous&rft.date=2024&rft_rights=NON-COMMERCIAL-REUSE-ONLY-(CC-BY-NC)&rft_subject=zika virus&rft_subject=mouse brain development&rft_subject=Medical virology&rft.type=dataset&rft.language=English Access the data
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The study aimed to investigate the utility of diceCT in detecting morphological changes with ZIKV-infection during development. The study used a previously published mouse model (Cowell, et al., 2023, DOI: 10.1007/s13365-023-01123-5), and has extended this to 10 dpi, equating to P4, P7 and P11 of mouse development. A file with the protocol for diceCT staining and imaging is herein. This Figshare site also contains images from diceCT scans of the brains of neonatal mice, compiled into videos (development - ui, ZKIV - containing 3, 6 and 10 dpi from individual uninfected and ZIKV mice; and unknown mixed cohort folders - from one litter with 3 ui and 4 ZIKV animals, in a blinded fashion). The computational segmenting and volume analysis performed on the brains is also available in a separate folder for both of these.

All original diceCT images are available on request.

Issued: 2024-08-19

Created: 2024-08-19

Subjects
Medical virology | mouse brain development | zika virus |

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url : https://figshare.com/authors/Jill_Carr/18870244

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