Developmental-associated dysregulation of innate anti-microbial immunity in early life as a determinant of susceptibility to atopic asthma [ 2012 - 2014 ]

Also known as: Developmental abnormalities in immune mechanisms that protect against respiratory infections and risk for development of asthma

Research Grant

[Cite as]

Researchers: Prof Patrick Holt (Principal investigator) ,  Dr Anthony Bosco Dr Danny Mok Dr Elysia Hollams

Brief description Previous NHMRC-sponsored research from the applicants has demonstrated that one of the strongest risk factors for subsequent development of asthma is having chest infections during infancy that are so severe that they trigger symptoms of fever and wheeze. It is not known what predisposes susceptible infants to these severe infections, and this project will attempt to define the mechanisms of susceptibility.

Funding Amount $AUD 570,334.32

Funding Scheme Project Grants

Notes Standard Project Grant

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