Developmental-associated dysregulation of innate anti-microbial immunity in early life as a determinant of susceptibility to atopic asthma [ 2012 - 2014 ]

Research Grant

Researchers: Prof Patrick Holt (Principal investigator) ,  Dr Anthony Bosco ,  Dr Danny Mok ,  Dr Elysia Hollams

Brief description Previous NHMRC-sponsored research from the applicants has demonstrated that one of the strongest risk factors for subsequent development of asthma is having chest infections during infancy that are so severe that they trigger symptoms of fever and wheeze. It is not known what predisposes susceptible infants to these severe infections, and this project will attempt to define the mechanisms of susceptibility.

Funding Amount $AUD 570,334.32

Funding Scheme Project Grants

Notes Standard Project Grant