grant

Development of a specific activin antagonist for therapeutic applications [ 2011 - 2014 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1006488]

Researchers: A/Pr Craig Harrison (Principal investigator) ,  Prof Katherine Loveland

Brief description Activin is a key regulator of homeostasis in several organs and tissues, including ovaries, testes, liver and skin, and alterations in activin�s activity can result in fibrosis, cachexia and cancer. In this grant we propose to develop a specific activin antagonist by modifying the activin A propeptide. This novel reagent could be used to promote liver growth in severe hepatic disease and prevent fibrosis in numerous tissues.

Funding Amount $AUD 504,287.27

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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