Development of site-specific predictive assay for periodontal disease progression using mass spectrometric &RT- PCR Anal [ 2002 - 2006 ]

Research Grant

Researchers: Prof Eric Reynolds (Principal investigator) ,  A/Pr Neil O'Brien-Simpson ,  Dr Nada Slakeski ,  Gert Talbo ,  Mr Geoffrey Adams
View all 7 related researchers

Brief description In this project new DNA-based technology will be developed to determine the numbers of specific bacteria in the dental plaque of patients. The project will also use new mass spectrometric analysis techniques for the determination of compounds in gingival crevicular fluid, an exudate from the gums. These two techniques will be used in a clinical trial to determine if periodontal (gum) disease progression can be predicted by changes in the numbers of bacteria or in the composition of gingival crevicular fluid. This could provide insight into the development of periodontal disease and lead to new preventive and treatment regimes.

Funding Amount $AUD 150,000.00

Funding Scheme NHMRC Strategic Awards

Notes Oral Health Research