Development of a serum based test for aggressive prostate cancer. [ 2005 - 2006 ]

Research Grant

Researchers: Prof Gail Risbridger (Principal investigator) ,  Dr Sally Mellor

Brief description Prostate cancer is relatively slow growing, taking decades to reach clinical significance. A critical phase in the progression of prostate cancer is the transformation from latent (or dormant) to aggressive tumours; hence the saying that many men die with prostate cancer, rather than of prostate cancer. We aim to develop a test utilising inhibin-activin proteins as surrogate markers of aggressive disease based on our previous studies of a significant correlation between the expression of inhibins in tissues from men with high grade prostate cancer. This study aims to validate the correlation using serum rather than a tissue based assay.

Funding Amount $AUD 144,950.00

Funding Scheme NHMRC Development Grants

Notes Development Grant