Development of Reversible Inhibitors of Factor XIa [ 2012 - 2014 ]

Research Grant

Researchers: Prof Ronald Quinn (Principal investigator) ,  A/Pr Mark Coster ,  Prof Susan Charman

Brief description Blood usually clots in response to injury, but unwanted clots can cause thrombosis, as well as leading to stroke and heart disease. Existing drugs to treat thrombosis suffer from drawbacks such as invasive monitoring, interaction with diet and other medicines, and bleeding complications. New drugs are clearly needed. Our expert group of researchers will discover new anti-thrombotic compounds based upon our previous identification of natural products with anticoagulant properties.

Funding Amount $AUD 444,318.62

Funding Scheme Project Grants

Notes Standard Project Grant