Development of resonance energy transfer technologies to detect GPCR heterodimer complexes in living cells [ 2008 - 2009 ]

Research Grant

Researchers: Karin Eidne (Principal investigator) ,  A/Pr Kevin Pfleger

Brief description G-protein coupled receptors are proteins at the surface of most cells in the body. They bind to drugs, transmitting signals into cells that change what cells are doing. Recent research indicates that different types of these proteins can interact with each other and when one of these protein combinations binds a drug, it acts differently to when the proteins act separately. The aim of our project is to find out which protein combinations exist and to find drugs that bind to them specifically.

Funding Amount $AUD 205,555.10

Funding Scheme NHMRC Development Grants

Notes Development Grant