grant

Development of pthaladyn-based dynamin I-selective inhibitors for treatment of epilepsy [ 2011 - 2013 ]

Also known as: New antiepileptic drugs that only act during seizure

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1017063]

Researchers: Prof Adam Mccluskey (Principal investigator) ,  A/Pr Megan Chircop Dr Jennette Sakoff Prof Phillip Robinson Prof Terence O'Brien

Brief description About 1% of the World�s population suffers from epilepsy; 30% fail to respond to anti-epileptic drugs (AED). Current AED development pathways have changed little in the past 20 years with the majority of current AEDs dampening the release of crucial chemical signals 24/7. Our new drugs, which inhibit a protein called dynamin, are only recruited at the onset of a seizure. Our approach will significantly enhance the day to day lives of those afflicted by epilepsy.

Funding Amount $AUD 564,310.34

Funding Scheme NHMRC Development Grants

Notes Development Grant

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Identifiers
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ACN 633 798 857