Development of potent and selective blockers of acid sensing ion channels for the treatment of pain [ 2011 - 2013 ]

Research Grant

Researchers: Prof Glenn King (Principal investigator) ,  Dr Lachlan Rash ,  Prof Alan Mark ,  Prof Matthew Cooper ,  Prof Paul Alewood

Brief description More than three million Australians suffer from chronic pain, and there are few effective drugs available for treating this condition. A 2007 Access Economics Report estimated the economic burden of chronic pain in Australia at $34.3 billion. Acid-sensing ion channels (ASICs) are a recently discovered family of proteins that play a key role in sensing pain. The goal of this project is to develop potent blockers of these channels that can be used to treat patients suffering from persistent pain.

Funding Amount $AUD 578,704.76

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant