grant

Development of Platelet-Targeted Nanoparticles for Magnetic Resonance Imaging towards the Detection of Thrombi/Emboli and Vulnerable Atherosclerotic Plaques [ 2011 - 2013 ]

Also known as: Platelet-Targeted MRI Nanoparticles

Funded by National Health and Medical Research Council
Managed by Baker IDI Heart and Diabetes Institute
Managed by International Diabetes Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1017670]

Researchers: Prof Karlheinz Peter (Principal investigator) ,  A/Pr Christoph Hagemeyer ,  Dr Guy Krippner ,  Dr Tim Adams

Brief description Heart attack, stroke and pulmonary embolism typically strike without warning and either kill patients or cause devastating disabilities. Currently, we do not have diagnostic methods to identify patients and the blood vessels at risk. We have developed a new innovative MRI nanoparticle directed against activated platelets for the detection of _at risk� blood vessels. The current funding is requested to optimise the manufacture of this targeted MRI nanoparticle and to undertake the animal studies required to enter early stage clinical trials.

Funding Amount $AUD 606,524.25

Funding Scheme NHMRC Development Grants

Notes Development Grant

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Subjects
Cardiorespiratory Medicine and Haematology | Cardiology (Incl. Cardiovascular Diseases) | Medical and Health Sciences | inflammation | magnetic resonance imaging (MRI) | myocardial infarction | nanotechnology | plaque rupture | platelets | pulmonary embolism | stroke | thrombosis | vascular occlusion |
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