DEVELOPMENT OF A NOVEL BIOMATERIAL FOR BONE TISSUE ENGINEERING [ 2003-01-01 - 2005-12-31 ]

Research Grant

Researchers: A/Prof Victor Nurcombe (Chief Investigator) ,  Prof Mathias Trau (Chief Investigator) ,  Professor Lisbeth Grondahl (Chief Investigator) ,  Professor Lisbeth Grondahl (Chief Investigator) ,  Professor Simon Cool (Chief Investigator)

Brief description DEVELOPMENT OF A NOVEL BIOMATERIAL FOR BONE TISSUE ENGINEERING. Tissue engineering of bone is emerging as a viable therapy for treating large defects in load-bearing bone. We wish to develop methods for combining novel heparan sulphate molecules (known to deliver growth factors to cell surfaces and thereby cause changes in bone cell phenotype) with load-bearing, macro-porous, biodegradable mineral/polymer biomaterials. Through the study of release profiles, protein adsorption and cell responses to these derivatised biomaterials, a novel approach to bone replacement materials can be developed.

Funding Amount $255,000

Funding Scheme Discovery Projects

View this grant in the ARC Data Portal