Development of Novel Antimicrobial Agents [ 2005 - 2007 ]

Research Grant

Researchers: Prof Staffan Kjelleberg (Principal investigator) ,  A/Pr Scott Rice ,  Emma Hume ,  Prof Allan Cripps ,  Prof Mark Willcox
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Brief description The Team brings together a unique grouping of people with backgrounds in molecular biology, medical microbiology, microbiology, marine ecology and immunology to tackle a significant health problem infections caused by bacteria. Using a novel approach, based on understanding how marine organisms specifically interfere with bacterial colonisation, the Team over the past seven years has identified a group of compounds that represent a novel group of antibiotics. Publications and patenting by the Team has demonstrated that the Team is at the forefront of research in this area. The novel antibiotics work by preventing bacteria sticking to surfaces and by preventing the bacteria from releasing toxins. The studies will concentrate on those bacteria that produce infections in the lungs (acute pneumonia), eyes (corneal infection), ear (middle ear disease), and abscesses.

Funding Amount $AUD 469,500.00

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant