Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/546243]Researchers: Prof Henry Krum (Principal investigator) , A/Pr Bing Wang , Prof Peter Scammells
Brief description There is an unmet need for safe and effective anti-inflammatory drugs. Because P38 MAPK intracellular signalling modulates multiple pro-inflammatory cytokine actions, it appears to be an ideal candidate pathway. P38 inhibitors have been limited by their toxicity within hepatocytes. The aim of this program therefore is to develop agents with enhanced P38 MAPK inhibitory effects as well as reduced liver toxicity based on known structure activity relationships.
Funding Amount $AUD 200,600.00
Funding Scheme NHMRC Development Grants
Notes Development Grant
- nhmrc : 546243
- PURL : https://purl.org/au-research/grants/nhmrc/546243
