Development of monoclonal antibody therapy for treating wounds [ 2010 - 2013 ]

Research Grant

Researchers: Prof Allison Cowin (Principal investigator) ,  Dr Ian Nicholson ,  Prof Heddy Zola

Brief description Chronic wounds, diabetic ulcers, injuries in response to trauma, burns and scalds form a medical need which will only expand as the population ages and the diabetic epidemic grows. In our studies, we have shown that Flightless I (Flii), an actin-remodelling protein, is a negative regulator of wound healing. We are developing monoclonal antibodies as a new therapy for reducing Flii levels in wounds which leads to improved wound repair outcomes.

Funding Amount $AUD 573,354.44

Funding Scheme NHMRC Development Grants

Notes Development Grant