Development of modified IGF-binding proteins as novel anti-cancer chemotherapeutics [ 2005 - 2005 ]

Research Grant

Researchers: Prof John Wallace (Principal investigator) ,  Prof Grant Booker

Brief description We propose to enhance the effectiveness of current anti-cancer treatments by co-administering a protein to sequester growth factors that promote the resistance of cancer cells to chemotherapy. We aim to achieve improved destruction of breast and colorectal cancers but with reduced adverse side effects. Our in vitro data show the effectiveness of this novel co-therapeutic which is a modified form of a natural carrier protein for these growth factors. This application seeks funding to enable proof of concept in vivo in order to attract commercial funding for clinical trials.

Funding Amount $AUD 77,375.00

Funding Scheme NHMRC Development Grants

Notes Development Grant