Development of anti-CXCR7 mAbs for the treatment of fibrosis [ 2010 - 2012 ]

Research Grant

Researchers: Prof Charles Mackay (Principal investigator) ,  Dr Frederic Sierro ,  Prof Fabienne Mackay

Brief description Fibrosis is a serious biological process that occurs in many disease conditions, including cancer, inflammation and infections. We have produced antibodies to CXCR7, and these antibodies completely inhibit fibrosis in a mouse model. We plan to develop these antibodies in to a suitable drug for human clinical trials.

Funding Amount $AUD 399,998.34

Funding Scheme NHMRC Development Grants

Notes Development Grant