grant

Developing new therapies to combat tuberculosis through inhibition of vitamin B5 metabolism in the organism that causes the disease [ 2011 - 2017 ]

Also known as: 5026233

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/GNT1016357]

Researchers: Dr Christina Spry (Principal investigator)

Brief description The metabolism of vitamin B5 by pathogenic microorganisms has been recognised as an attractive target for developing drugs to combat various infectious diseases. The aim of the proposed work is to develop inhibitors of vitamin B5 metabolism in the bacterium that causes tuberculosis, using a powerful, multidisciplinary approach known as “fragment-based drug discovery”. This work is likely to yield potent inhibitors of the target bacterium, which could ultimately be used to treat tuberculosis.

Funding Amount $AUD 311,760.00

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF

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Identifiers
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ACN 633 798 857