grant

Determining the unique processes that control memory B cell-mediated secondary antibody responses [ 2017 - 2020 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1124681]

Researchers: A/Pr Tri Phan (Principal investigator) ,  A/Pr Fabio Luciani Dr Cindy Ma Dr John Zaunders

Brief description Vaccines educate the immune system by training memory cells to make neutralizing antibodies when it re-encounters the pathogen. However, where and how these memory cells are activated in the secondary antibody response in immune animals remain unknown. Here we use cutting edge technologies to fate map and gene profile memory cells and determine the molecular switches that control the secondary antibody response. This will be complemented by human vaccine studies.

Funding Amount $AUD 874,970.57

Funding Scheme Project Grants

Notes Standard Project Grant

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