Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1060303]Researchers: Dr Cindy Ma (Principal investigator)
Brief description Autosomal recessive hyper IgE (AR-HIES) syndrome due to mutations in DOCK8 is a rare primary immunodeficiency whereby patients present with susceptibility to severe and recurrent viral infections as well as an increased risk of developing cancer, severe food and environmental allergies, and atopic disease characterised by hyper IgE and extreme eosinophilia. This grant will investigate how abnormal DOCK8 function in CD4+ T cells and B cells contributes to disease pathogenesis in AR-HIES patients.
Funding Amount $AUD 512,600.68
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1060303
- PURL : https://purl.org/au-research/grants/nhmrc/1060303