grant

Determining the bacterial contributions to tuberculosis and identification of drug targets [ 2011 - 2014 ]

Also known as: Tuberculosis: genes to drugs

Funded by National Health and Medical Research Council
Managed by The University of Queensland
Managed by University of Queensland
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1012865]

Researchers: Dr Nicholas West (Principal investigator)

Brief description Serious issues of drug resistance have emerged in tuberculosis prevention and are placing enormous pressure on global health systems. We have identified an enzyme of M. tuberculosis that is essential for its survival. This project will develop potent inhibitory compounds for this enzyme. Further, we will identify new drug targets through a screen to specifically identify the genes of the organism essential for its survival in the body. This information will be used to develop new TB drugs.

Funding Amount $AUD 443,946.44

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF

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Subjects
Medical and Health Sciences | Medical Microbiology | Medical Bacteriology | bacterial genetics | bacterial pathogenesis | chronic infection | drug development | drug discovery | respiratory diseases | tuberculosis | virulence factors |
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