grant

To determine whether Myc-driven transformation in haematopoietic cell lineages is dependent on high-levels of Myc protein expression. [ 2014 - 2019 ]

Also known as: To determine the dependance of blood cancers on high levels of Myc protein.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1072477]

Researchers: Dr Megan Bywater (Principal investigator)

Brief description Myc is an essential cellular protein but is also a common drive of cancer in multiple tissues. In blood cancers Myc is frequently overexpressed. In contrast, Myc is rarely overexpressed in early stage solid cancers, although often elevated levels at later stages. We will employ unique models of cancer in which Myc can be activated at different set levels at different times during blood cell development to address what the specific contributions of different levels of Myc are in the evolution of blood cancers.

Funding Amount $AUD 371,896.66

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF

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Identifiers
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ACN 633 798 857