grant

Determinants of occurrence and progression of aortic stenosis in bicuspid and tricuspid valves. [ 2010 - 2013 ]

Also known as: Progression of Aortic Stenosis.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/627245]

Researchers: Prof John Horowitz (Principal investigator)

Brief description Aortic stenosis (AS) is a major cause of cardiac failure and mortality in ageing Australians. AS occurs both in bicuspid aortic valves (BAV;0.5-1% of the population) and in anatomically tricuspid valves. There is an associated incremental risk of myocardial infarction. The research will investigate patients with BAV and with early AS in tricuspid valves, in order to examine the potential roles of loss of nitric oxide effect and of oxidant stress as predictors of AS development.

Funding Amount $AUD 546,394.32

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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