Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/572575]Researchers: Prof Geoffrey Shellam (Principal investigator) , A/Pr Alec Redwood , Dr Lee Smith
Brief description Human cytomegalovirus (HCMV) persists for extended periods in the salivary gland, an organ of viral transmission. It is not clear how the virus avoids immune mediated control in this tissue. This aspect of viral pathology will be assessed in a mouse model using two strains of murine CMV which exhibit marked differences in salivary gland persistence. The role of tissue tropism (inhibition of apoptosis), viral immune evasion and host immunity in salivary gland persistence will be studied.
Funding Amount $AUD 566,308.79
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 572575
- PURL : https://purl.org/au-research/grants/nhmrc/572575
