Designer DNA-binding proteins targeting methylated DNA for research and therapeutic purposes [ 2012 - 2014 ]

Also known as: The design of DNA-binding proteins targeted to methylated DNA

Research Grant

[Cite as]

Researchers: Prof Joel Mackay (Principal investigator) ,  A/Pr David Segal Prof John Rasko

Brief description A number of human genes function to suppress the onset or progression of cancer. In cancer sufferers, these genes are often switched off. The aim of this project is to engineer designer protein molecules that will be able to switch these tumor suppressor genes on again in a selective manner. Because the switching off of tumor suppressor genes is common to all forms of cancer, the new technology created in this work will potentially benefit patients suffering from any of a wide range of cancers.

Funding Amount $AUD 583,444.68

Funding Scheme Project Grants

Notes Standard Project Grant

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