Design and delivery of peptide-based anti-cancer Grb7 inhibitors [ 2013 - 2016 ]

Research Grant

Researchers: A/Pr Jacqueline Wilce (Principal investigator) ,  Dr Stephanie Pero ,  Prof Patrick Perlmutter

Brief description The Grb7 protein is overproduced in many types of cancer cells and plays a role in cancer cell growth and spread. The current proposal builds upon the discovery of a peptide-based Grb7 inhibitor that has anti-cancer activity. This proposal is to prepare more potent inhibitor molecules that can efficiently reach the target cancer cells. Such molecules will be used for the study of Grb7 and for the development of a new Grb7-based anti-cancer drug therapy.

Funding Amount $AUD 603,126.54

Funding Scheme Project Grants

Notes Standard Project Grant