A DENDRITIC SUBSTRATE FOR THE CHOLINERGIC CONTROL OF NEOCORTICAL OUTPUT [ 2018 - 2021 ]

Research Grant

Researchers: Prof Stephen Williams (Principal investigator) ,  Prof Elizabeth Coulson

Brief description The forebrain cholinergic system controls neocortical activity and cognitive function. This project will investigate the mechanisms by which the cholinergic system controls neocortical circuit activity in rodent models using advanced optical and electrical recording methods. The results will provide a foundation for the understanding of how dysfunction of the cholinergic system results in cognitive decline in humans, and identify new targets for improved treatment of human cognitive impairment.

Funding Amount $AUD 910,916.76

Funding Scheme Project Grants

Notes Standard Project Grant